Thursday, 31 January 2008

dna - Is telomere shortening consistant over consecutive cell divisions from zygote to a differentiated cell?

Considering the complexity of embryogenesis, a temporal referance would be helpful to coordinate the developmental sequences during embryogenesis and fetal development which is to be completed within the gestation period. Can telomere shortening if consistant be used as a reference by every cell to do what it is destined to do at particular time frame? This is without considering the influence of telomerase etc.



This is also without prejudice to the role of DNA directed molecular signalling.



To repeat the question is telomere shortening consistant over consecutive cell divisions from zygote to a differentiated cell? If so can it function as temporal control of embryogenesis?

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