Tuesday 31 May 2016

neuroscience - SPINAL CORD: Do the axons from white matter synapse with the cell bodies in grey matter?

Here is a great diagram (from here) that outlines all of the different white matter tracts running up (blue) and down (red) the cord.
enter image description here



The portion in the center, as you have found in your research, is the gray matter. In there are the different interneurons (cells that exist in the network to integrate information from descending controls and do further processing on it) and all of the different motor neurons. The corticospinal tract descends to the appropriate level (for example, a neuron in charge of moving your arm, to keep it simple, will have a cell body in the brain, and descend to the thoracic level), enters into the gray matter and either synapse on an interneuron or directly onto a motor neuron).



The sensory neurons are a slightly different animal. Some (pseudo-unipolar cells) have what are basically two "legs", one that runs out into the periphery, which will take the signal from something like a Pacinian corpuscle in the skin, propagates a signal to the cell body, which is outside of the spinal cord in the dorsal root (see below), and the other "leg" runs all the way up the dorsal column into the medulla of the brainstem.



enter image description here



from here



So that should give you some idea of the two major tracts. To see some of the finer detail, you can look into the different layers (laminae) that the gray matter is composed of, so that you can trace the connections all the way in.

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